Publications
A. Patel, R. G. Thakar, M. Chown, P. Ayala, T. A. Desai, and S. Kumar (2009). Biophysical Mechanisms of Single-Cell Interactions with Microtopographical Cues. Biomedical Microdevices (in press).
T. A. Ulrich, A. Jain, K. Tanner, J. L. MacKay, S. Kumar (2009). Probing cellular mechanobiology in three-dimensional culture with collagen-agarose matrices. Biomaterials (PDF).
S. Sen and S. Kumar (2009). Combining mechanical and optical approaches to dissect cellular mechanobiology. Journal of Biomechanics (PDF).
T. A. Ulrich and S. Kumar. Mechanobiology in health and disease in the central nervous system. Book chapter for Mechanobiology Handbook, CRC Press-Taylor and Francis Group, LLC (scheduled for publication in 2010).
S. Kumar, P. Parot, J. L. Pellequer (2009). Second international AFM Biomed conference on AFM in the life sciences and medicine, 16-18 October 2008, Monterey, CA, USA [editorial]. Journal of Molecular Recognition 22: 345-346. (PDF)
D. J. D'Sa, E. M. de Juan Pardo, R. de las Rivas Astiz, S. Sen, and S. Kumar (2009). High-throughput indentational elasticity measurements of hydrogel extracellular matrix substrates. Applied Physics Letters 95:63701 1-3 (PDF).
S. Sen and S. Kumar (2009). Cell-matrix de-adhesion dynamics reflect contractile mechanics. Cellular and Molecular Bioengineering 2: 218-230. (PDF).
T. A. Ulrich, E. M. de Juan Pardo, and S. Kumar (2009). The mechanical rigidity of the extracellular matrix regulates the structure, motility, and proliferation of glioma cells. Cancer Research 69: 4167-4174. (PDF).
A. J. Keung, K. E. Healy, S. Kumar, and D. V. Schaffer (2009). Biophysics and dynamics of natural and engineered stem cell microenvironments. Wiley Interdisciplinary Reviews: Systems Biology and Medicine (PDF).
S. Kumar and V. M. Weaver (2009). Mechanics, malignancy, and metastasis: The force journey of a tumor cell. Cancer and Metastasis Reviews 28:113-127. (PDF)
Luo, Y., Xu, X., Lele, T., Kumar, S., and Ingber, D.E. (2008). A multi-modular tensegrity model of an actin stress fiber. Journal of Biomechanics 41: 2379-2387. (PDF)
R. G. Thakar, M. G. Chown, A. Patel, L. Peng, S. Kumar, and T. A . Desai (2008). Contractility-dependent modulation of cell proliferation and adhesion by microtopographical cues. Small 4: 1416-1424. (PDF)
R. J. Mannix*, S. Kumar*, F. Cassiola, M. Montoya-Zavala, E. Feinstein, M. Prentiss, and D. E. Ingber (2008). Nanomagnetic actuation of receptor-mediated signal transduction. Nature Nanotechnology 3: 36-40 [*equal contribution]. (PDF) (Nature Nanotechnology Highlight)
S. Kumar and P. R. Leduc (2007). Dissecting the molecular basis of the mechanics of living cells. Experimental Mechanics 49: 11-23 [published online August 10, 2007; in print February 2009]. (PDF).
M. Chown and S. Kumar (2007). Imaging and manipulating the structural machinery of living cells on the micro- and nanoscale. International Journal of Nanomedicine 2: 333-344 (PDF) .
T. P. Lele, J. Sero, B. Matthews, S. Kumar, N. Xia, M. Montoya-Zavala, T. Polte, D. R. Overby, N. Wang, and D. E. Ingber (2007). Tools to study cell mechanics and mechanotransduction. In Cell Mechanics (Academic Press, Y.-L. Wang and D. E. Discher, Eds.) Methods in Cell Biology 83: 435-464. (PDF)
T. P. Lele and S. Kumar (2007). Brushes, cables, and anchors: Recent insights into multiscale assembly and mechanics of cellular structural networks. Cell Biochemistry and Biophysics 47: 348-360 (PDF).
C. P. Brangwynne, F. C. MacKintosh, S. Kumar, N. A. Geisse, J. Talbot, L. Mahadevan, K. K. Parker, D. E. Ingber, and D. A. Weitz (2006). Microtubules can bear enhanced compressive loads in living cells because of lateral reinforcement. Journal of Cell Biology 173: 733-741. (PDF) (JCB Highlight) (Current Biology Dispatch)
S. Kumar, I.Z. Maxwell, A. Heisterkamp, T.R. Polte, T.P. Lele, M. Salanga, E. Mazur, and D.E. Ingber (2006). Viscoelastic retraction of single living stress fibers and its impact on cell shape, cytoskeletal organization and extracellular matrix mechanics. Biophysical Journal 90: 3762-3773. (PDF)
T. P. Lele, J. Pendse, S. Kumar, M. Salanga, J. Karavitis, and D. E. Ingber (2006). Mechanical forces alter zyxin unbinding kinetics within focal adhesions of living cells. Journal of Cellular Physiology 207: 187-194. (PDF)
A. Heisterkamp, I. Z. Maxwell, E. Mazur, J. M. Underwood, J. A. Nickerson, S. Kumar, and D. E. Ingber (2005). Pulse energy-dependence of subcellular ablation by femtosecond laser pulses. Optics Express 13: 3690-3696. (PDF)
S. Kumar and J. H. Hoh (2004). Modulation of repulsive forces between neurofilaments by sidearm phosphorylation. Biochemical and Biophysical Research Communications 324: 489-496. (PDF)
R. Mukhopadhyay, S. Kumar, and J. H. Hoh (2004). Molecular mechanisms for organizing the neuronal cytoskeleton. BioEssays 26: 1017-1025. (PDF)
S. Kumar, X. Yin, B. D. Trapp, M. E. Paulaitis, and J. H. Hoh (2002). Role of long-range repulsive forces in organizing axonal neurofilament distributions: Evidence from mice deficient in myelin-associated glycoprotein. Journal of Neuroscience Research 68: 681-690. (PDF)
J. Schneider, P. Berndt, K. Haverstick, S. Kumar, S. Chiruvolu, and M. Tirrell (2002). Surface force measurements of electrostatic and hydrogen-bonding interactions between bilayers of glycine amphiphiles. Langmuir 18: 3923-3931. (PDF)
S. Kumar, X. Yin, B. D. Trapp, J. H. Hoh, and M. E. Paulaitis (2002). Relating interactions between neurofilaments to the structure of axonal neurofilament distributions through polymer brush models. Biophysical Journal 82: 2360-2372. (PDF)
S. Kumar and J. H. Hoh (2001). Probing the machinery of intracellular trafficking with the atomic force microscope. Traffic 2: 746-756. (PDF)
S. Kumar and J. H. Hoh (2000). Direct visualization of vesicle-bilayer complexes by atomic force microscopy. Langmuir 16: 9936-9940. (PDF)
J. Schneider, P. Berndt, K. Haverstick, S. Kumar, S. Chiruvolu, and M. Tirrell (1998). Force and adhesion measurements between hydrogen-bonded layers of glycine-functionalized amphiphiles. Journal of the American Chemical Society 120: 3508-3509. (PDF)
