Platelet mechanosensing of substrate stiffness during clot formation mediates adhesion, spreading, and activation.

Y. Qiu, A. C. Brown, D. R. Myers, Y. Sakurai, R. G. Mannino, R. Tran, B. Ahn, E. T. Hardy, M. F. Kee, S. Kumar, G. Bao, T. H. Barker, and W. A. Lam  (2014).  Platelet mechanosensing of substrate stiffness during clot formation mediates adhesion, spreading, and activation.  Proceedings of the National Academy of Sciences (PNAS) 111: 14430 – 14435 (PDF).